CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration
Abstract Directed cell migration requires sustained cell polarisation.In Womens Leggings migrating cortical interneurons, nuclear movements are directed towards the centrosome that organises the primary cilium signalling hub.Primary cilium-elicited signalling, and how it affects migration, remain however ill characterised.Here, we show that alterin